MassAITC Webinar | Best Practices for Digital Phenotyping Research in Aging Populations

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Speaker

Raeanne Moore, PhD. Professor of Psychiatry, University of California San Diego (UCSD) and Co-Founder of NeuroUX

Abstract

Digital phenotyping is transforming aging research by enabling high-frequency, real-world measurement of cognition, behavior, symptoms, and context through smartphones, wearables, and passive sensing technologies. This talk will review how digital health tools can complement traditional clinic-based assessments by capturing intraindividual variability, diurnal patterns, environmental influences, and subtle changes in cognitive and functional performance that may signal risk for neurodegenerative disease. Using examples from studies of healthy aging, MCI, Alzheimer’s disease risk, dementia caregiving, and related clinical populations, the talk will highlight best practices for designing digital phenotyping protocols, balancing participant burden with data richness, maximizing adherence, integrating active cognitive assessments with passive data streams and biomarkers, and applying analytic approaches that distinguish within-person change from between-person differences. The session will emphasize opportunities for digital phenotyping to improve early detection, clinical trial endpoints, remote monitoring, and personalized care for older adults.

Speaker Bio

Dr. Raeanne Moore is a clinical neuropsychologist and Professor of Psychiatry at the University of California San Diego (UCSD), where she directs the Mental Health Technology Center (MHTech). Her research leverages digital health technologies to improve the assessment of cognition and real-world functional outcomes. Dr. Moore’s work also applies machine learning and artificial intelligence to identify digital biomarkers that may predict cognitive decline. Further, she is a co-founder of NeuroUX, a digital health platform that disseminates digital phenotyping tools for clinical trials, research, and clinical care. Grounded in clinical evidence and peer-reviewed research, these tools are used by research and clinical groups nationally and internationally to support mental health and cognitive testing in real-world settings.